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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKG All Species: 11.21
Human Site: S153 Identified Species: 20.56
UniProt: P49619 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49619 NP_001074213.1 791 89096 S153 P P V P R S S S S E S P V V Y
Chimpanzee Pan troglodytes XP_001152821 791 89168 S153 P P V P R S S S S E S P M V Y
Rhesus Macaque Macaca mulatta XP_001092912 791 89195 S153 P P V P R S S S S E S P V V Y
Dog Lupus familis XP_545239 790 88986 G152 N P V A P S P G S E S P I V Y
Cat Felis silvestris
Mouse Mus musculus Q91WG7 788 88505 K159 D A P V V Y L K D V V C Y L S
Rat Rattus norvegicus P49620 788 88503 A153 A P A S S S D A P I V Y L K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511802 697 78726 I113 L H E M M E E I D Y D H D G T
Chicken Gallus gallus XP_422650 933 102351 A259 A A P Q H P P A P L A Q V V Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696120 893 99287 S232 S P S P Q K G S P S P Q V V F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q01583 1211 132942 D264 A R K L S H F D P L T L K V P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03603 812 91362 K157 Q E P R I P L K P L I C T L S
Sea Urchin Strong. purpuratus XP_001197889 1217 132437 D556 R G S L A H P D V T N Q V V Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39017 728 79965 G144 C K C V S M V G F E H V V H Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 96.8 94 N.A. 89.7 88.2 N.A. 51.3 54.9 N.A. 59.2 N.A. 35.5 N.A. 46 38.3
Protein Similarity: 100 99.7 97.8 95.5 N.A. 94.1 93 N.A. 63.5 65.9 N.A. 72.7 N.A. 46.5 N.A. 63.2 48.8
P-Site Identity: 100 93.3 100 60 N.A. 0 13.3 N.A. 0 20 N.A. 33.3 N.A. 6.6 N.A. 0 20
P-Site Similarity: 100 100 100 66.6 N.A. 6.6 26.6 N.A. 0 33.3 N.A. 46.6 N.A. 13.3 N.A. 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 22.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 16 8 8 8 0 0 16 0 0 8 0 0 0 0 % A
% Cys: 8 0 8 0 0 0 0 0 0 0 0 16 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 16 16 0 8 0 8 0 8 % D
% Glu: 0 8 8 0 0 8 8 0 0 39 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 8 % F
% Gly: 0 8 0 0 0 0 8 16 0 0 0 0 0 8 0 % G
% His: 0 8 0 0 8 16 0 0 0 0 8 8 0 8 0 % H
% Ile: 0 0 0 0 8 0 0 8 0 8 8 0 8 0 0 % I
% Lys: 0 8 8 0 0 8 0 16 0 0 0 0 8 8 0 % K
% Leu: 8 0 0 16 0 0 16 0 0 24 0 8 8 16 0 % L
% Met: 0 0 0 8 8 8 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 24 47 24 31 8 16 24 0 39 0 8 31 0 0 8 % P
% Gln: 8 0 0 8 8 0 0 0 0 0 0 24 0 0 8 % Q
% Arg: 8 8 0 8 24 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 16 8 24 39 24 31 31 8 31 0 0 0 16 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 8 0 8 0 8 % T
% Val: 0 0 31 16 8 0 8 0 8 8 16 8 47 62 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 8 0 8 8 0 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _